Antibody

PKC (pan), phos Ser660

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Clonality: polyclonal
Host: Rabbit
Source: Cell Signaling
Cat# 9371
Reference:
Townsend, 2007
Formulation: liquid, affinity purified, HEPES, saline, BSA, glycerol
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat

Immunogen/Epitope

immunogen = synthetic phospho-peptide, KLH coupled, corresp. to residues surrounding Ser660 of human PKC β II

Specificity

detects endogenous levels of PKC α, β I, β II, δ, ε, η and θ isoforms only when phosphorylated at a carboxy terminal residue homologous to serine 660 of PKC β II. This antibody does not detect PKC phosphorylated at other sites

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References

Paper Citations

  1. . Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem. 2007 Nov 16;282(46):33305-12. PubMed.

Further Reading

No Available Further Reading