Methods: ELISA, IP, WB
Source: Cell Signaling
Formulation: liquid, HEPES, saline, BSA, glycerol
Reacts in: Non-specific
immunogen = synthetic phospho-PKA substrate peptides (KLH coupled)
detects peptides and proteins containing a phospho serine/threonine residue with arginine at the -3 and -2 positions. It is a useful tool in identifying new substrates of PKA. The antibody recognizes other -3 arginine-bearing phospho-Ser/Thr peptides, such as substrate motifs for Akt and PKC, to a lesser extent. It does not recognize the nonphosphor substrate motif peptides
- Townsend M, Mehta T, Selkoe DJ. Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem. 2007 Nov 16;282(46):33305-12. PubMed.
No Available Further Reading