Antibody

p70 S6 Kinase phos Thr389 (108D2)

Clonality: monoclonal
Host: Rabbit
Isotype: IgG
Methods: WB
Source: Cell Signaling
Cat# 9234
Reference:
Zempel H, 2010
Formulation: liquid, HEPES, NaCl, BSA, glycerol
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

Immunogen = synthetic phospho-peptide corresp. to residues around Thr389 of human p70 S6 kinase

Specificity

detects endogenous levels of p70 S6 kinase only when phosphorylated at threonine 389; also detects p85 S6 kinase when phosphorylated at the analogous site (Thr412), and possibly S6KII phosphorylated at Thr401

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References

Paper Citations

  1. . Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.

Further Reading

No Available Further Reading