Antibody

p70 S6 Kinase phos Thr389

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Clonality: polyclonal
Host: Rabbit
Source: Cell Signaling
Cat# 9205
Reference:
Hoeffer, 2008
Formulation: liquid, protein-A and affinity purified, HEPES, saline, BSA, glycerol
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat

Immunogen/Epitope

immunogen = synthetic phospho-peptide (KLH-coupled) corresponding to residues around Thr389 of human p70 S6 kinase

Specificity

detects endogenous levels of p70 S6 kinase only when phosphorylated at Thr389; also detects p85 S6 kinase when phosphor. at the analogous site (Thr412) and possibly S6KII phosphor. at Thr401

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References

Paper Citations

  1. Hoeffer CA, Tang W, Wong H, Santillan A, Patterson RJ, Martinez LA, Tejada-Simon MV, Paylor R, Hamilton SL, Klann E. Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron. 2008 Dec 10;60(5):832-45. PubMed.

Further Reading

No Available Further Reading