NeuN (A60)

Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: IC, IF, IH, IP, WB
Source: Chemicon and Upstate are Millipore
Cat# MAB377
Veeraraghavalu, 2010
Heneka, 2010
He, 2009
Mallucci, 2007
Pereira, 2007
(unspecified formulation for
Burré J, 2010
Kapoor, 2010
Jäderstad, 2010
Wang, J, 2010
Demars, 2010
Loane, 2009
Varvel, 2009
Rose, 2009 )
Formulation: liquid, purified Ig, phosphate buffer, NaCl, azide<br />Also available prediluted, <a href="">IHR1001-6</a>
Reacts in: Avian (various), Primate (various), Chicken, Salamander, Ferret, Pig, Human, Mouse, Rat
others not tested


immunogen =
purified cell nuclei from mouse brain


reacts with most neuronal cell types; is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells

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Paper Citations

  1. . Presenilin 1 mutants impair the self-renewal and differentiation of adult murine subventricular zone-neuronal progenitors via cell-autonomous mechanisms involving notch signaling. J Neurosci. 2010 May 19;30(20):6903-15. PubMed.
  2. . Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. PubMed.
  3. . Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci. 2009 May 20;29(20):6545-57. PubMed.
  4. . Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice. Neuron. 2007 Feb 1;53(3):325-35. PubMed.
  5. . An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5638-43. PubMed.
  6. . Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science. 2010 Sep 24;329(5999):1663-7. PubMed.
  7. . Loss of thyroid hormone receptor β is associated with increased progenitor proliferation and NeuroD positive cell number in the adult hippocampus. Neurosci Lett. 2011 Jan 7;487(2):199-203. PubMed.
  8. . Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5184-9. PubMed.
  9. . Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6498-503. Epub 2010 Mar 15 PubMed.
  10. . Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice. J Neurosci Res. 2010 Aug 1;88(10):2103-17. PubMed.
  11. . Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nat Med. 2009 Apr;15(4):377-9. PubMed.
  12. . NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease. J Clin Invest. 2009 Dec;119(12):3692-702. PubMed.
  13. . Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. J Neurosci. 2009 Jan 28;29(4):1115-25. PubMed.

External Citations

  1. IHR1001-6

Further Reading

No Available Further Reading