Antibody

MAP2[2a, 2b, 2c] (HM-2)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Sigma Aldrich
Cat# M4403
References:
Andrews-Zwilling, 2010
Varvel, 2009
Ohsawa, 2008
Kalhoff, 2007
(all, unspecified formulation)
Giorgi, 2007
Formulation: ascites fluid, azide
Reactivity:
Reacts in: Bovine, Chicken, Quail, Human, Mouse, Rat

Immunogen/Epitope

immunogen = rat brain MAPs

Specificity

all forms of MAP2; not tubulin, or any other maps; selective labeling of dendritic trees throughout the brain

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References

Paper Citations

  1. Andrews-Zwilling Y, Bien-Ly N, Xu Q, Li G, Bernardo A, Yoon SY, Zwilling D, Yan TX, Chen L, Huang Y. Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice. J Neurosci. 2010 Oct 13;30(41):13707-17. PubMed.
  2. Varvel NH, Bhaskar K, Patil AR, Pimplikar SW, Herrup K, Lamb BT. Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease. J Neurosci. 2008 Oct 22;28(43):10786-93. PubMed.
  3. Ohsawa I, Nishimaki K, Murakami Y, Suzuki Y, Ishikawa M, Ohta S. Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity. J Neurosci. 2008 Jun 11;28(24):6239-49. PubMed.
  4. Kallhoff V, Peethumnongsin E, Zheng H. Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease. Mol Neurodegener. 2007;2:6. PubMed.
  5. Giorgi C, Yeo GW, Stone ME, Katz DB, Burge C, Turrigiano G, Moore MJ. The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression. Cell. 2007 Jul 13;130(1):179-91. PubMed.

Further Reading

No Available Further Reading