Antibody

MAP2 (AP20)

Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: IH, WB
Source: Chemicon and Upstate are Millipore
Cat# MAB3418
References:
(unspecified formulation for:
Decker, 2010
Paula-Lima, 2010
He, 2009
Rose, 2009 )
Formulation: purified IgG, phosphate buffer, saline, azide.<br />Also available as AlexaFluor® 488 conjugate
Reactivity:
Reacts in: Bovine, Chicken, Quail, Human, Mouse, Rat, Xenopus
others not tested

Immunogen/Epitope

immunogen = bovine brain microtubule protein

Specificity

MAP2 in neuronal cell bodies and dendrites

Comments / Questions

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References

Paper Citations

  1. . Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons. J Neurosci. 2010 Jul 7;30(27):9166-71. PubMed.
  2. . Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF. Antioxid Redox Signal. 2011 Apr 1;14(7):1209-23. PubMed.
  3. . Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci. 2009 May 20;29(20):6545-57. PubMed.
  4. . Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. J Neurosci. 2009 Jan 28;29(4):1115-25. PubMed.

Further Reading

No Available Further Reading