Antibody

MAP2 (2a+2b) (AP-20)

Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: IB, IC
Source: Sigma Aldrich
Cat# M1406
References:
Zempel H, 2010
Song, 2002
Formulation: ascites fluid, azide
Reactivity:
Reacts in: Bovine, Quail, Salamander, Human, Mouse, Rat, Xenopus

Immunogen/Epitope

immunogen = bovine MAP2

Specificity

MAP2a and MAP2b; not MAP2c, MAP1, MAP5, tubulin, or tau

Comments / Questions

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References

Paper Citations

  1. . Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.
  2. . Astroglia induce neurogenesis from adult neural stem cells. Nature. 2002 May 2;417(6884):39-44. PubMed.

Further Reading

No Available Further Reading