Antibody
LRP, light chain (5A6)
Quick Links
Clonality: monoclonal
Host: Mouse
Isotype: IgG2
Source: Calbiochem EMD Biosciences
Cat# 438192
Reference:
Bell, 2009
Sagare, 2007
Formulation: liquid, NaCl, phosphate buffer, EDTA, no preservative
Reactivity:
Reacts in: Rabbit, Human, Mouse
Immunogen/Epitope
immunogen = purified, human placenta LRP
Specificity
recognizes the ~85 kDa LRP light chain protein under non-reducing conditions
References
Paper Citations
- Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV. SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nat Cell Biol. 2009 Feb;11(2):143-53. PubMed.
- Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, Marky A, Lenting PJ, Wu Z, Zarcone T, Goate A, Mayo K, Perlmutter D, Coma M, Zhong Z, Zlokovic BV. Clearance of amyloid-beta by circulating lipoprotein receptors. Nat Med. 2007 Sep;13(9):1029-31. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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