Antibody
LRP, heavy chain (8G1)
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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Calbiochem EMD Biosciences
Cat# 438190
Reference:
Sagare, 2007
Formulation: liquid, NaCl, phosphate buffer, no preservative
Reactivity:
Reacts in: Human
Immunogen/Epitope
immunogen = native LRP from human placenta
Specificity
recognizes the ~515 kDa LRP heavy chain protein under non-reducing conditions; inhibits the binding of LRP to α2-macroglobulin
References
Paper Citations
- Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, Marky A, Lenting PJ, Wu Z, Zarcone T, Goate A, Mayo K, Perlmutter D, Coma M, Zhong Z, Zlokovic BV. Clearance of amyloid-beta by circulating lipoprotein receptors. Nat Med. 2007 Sep;13(9):1029-31. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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