Antibody
Lamin-A
Quick Links
Clonality: polyclonal
Host: Rabbit
Source: Sigma Aldrich
Cat# L1293
Reference:
D'Angelo, 2009
Formulation: liquid, affinity isolated, PBS, azide
Reactivity:
Reacts in: Human, Mouse, Rat
Immunogen/Epitope
immunogen = synthetic peptide corresp. to amino acid residues
598-611 of human lamin A with a C-terminal added
cysteine, conj. to KLH, as immunogen
Specificity
recognizes lamin A. (~ 70 kDa); additional bands at 45-50 kDa may appear in some preparations, which may represent cleaved fragments of lamin A; antibody does not recognize lamin C
References
Paper Citations
- D'Angelo MA, Raices M, Panowski SH, Hetzer MW. Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells. Cell. 2009 Jan 23;136(2):284-95. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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