Methods: IC, IF, WB
Source: Cell Signaling
Formulation: liquid, HEPES, saline, BSA, glycerol
Reacts in: Human
immunogen = synthetic phospho peptide (KLH-coupled) corresp. to residues surrounding Tyr1361 of human insulin receptor β
detects transfected levels of insulin receptor β only when phosphor. at Tyr1361. It slightly cross-reacts with activated IGF-I receptor, but does not cross with other activated tyrosine kinases
- Townsend M, Mehta T, Selkoe DJ. Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem. 2007 Nov 16;282(46):33305-12. PubMed.
No Available Further Reading