Antibody

Insulin Receptor β (4B8)

Clonality: monoclonal
Host: Rabbit
Isotype: IgG
Methods: FC, IP, WB
Source: Cell Signaling
Cat# 3025
Reference:
Townsend, 2007
Formulation: liquid, HEPES, saline, BSA, glycerol
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = synthetic peptide (KLH-coupled) corresp. to residues surrounding Tyr960 of human insulin receptor β

Specificity

detects endogenous levels of total insulin receptor β, 95 kDa by WB. It does not cross-react with IGF-IR β

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References

Paper Citations

  1. . Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem. 2007 Nov 16;282(46):33305-12. PubMed.

Further Reading

No Available Further Reading