Antibody

Iba-1

Clonality: polyclonal
Host: Rabbit
Methods: WB
Source: Wako Chemicals
Cat# 016-20001
References:
Lewis TL, 2010
Mildner, 2008
Formulation: sera, affinity purified, TBS, no preservatives or stabilizers
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

Immunogen = synthetic peptide corresponding to the C-terminus of Iba-1 (Ionized calcium binding adaptor molecule 1)

Specificity

Microglia and macrophages, but no cross reactivity with neurons and astrocytes

Comments / Questions

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References

Paper Citations

  1. . Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease. J Biol Chem. 2010 Nov 19;285(47):36958-68. Epub 2010 Sep 16 PubMed.
  2. . Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci. 2007 Dec;10(12):1544-53. PubMed.

Further Reading

No Available Further Reading