Antibody

Huntingtin(MW7)

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Clonality: monoclonal
Source: (Jan Ko, Susan Ou and Paul H. Patterson, 216-76, Biology Division, California Institute of Technology)
used in paper by Khoshman, 2002
Reactivity:
Reacts in: Human, Mouse
reference:<br />Ko J, Ou S, Patterson P H. <em>Brain Research Bulletin</em> 56:319-329, 2001

Immunogen/Epitope

polyP domain of Htt

Specificity

Huntingtinstains htt in the perinuclear region as well in the nuclear inclusions formed by mutant htt; can differentiate transgenic from WT mice by staining nuclear inclusions in R6/2 brain

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References

Paper Citations

  1. . Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):1002-7. PubMed.

Other Citations

  1. Paul H. Patterson

Further Reading

No Available Further Reading