Antibody

Huntingtin (1HU-4C8)

Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: ELISA, IC, IH, IP, WB
Source: Chemicon and Upstate are Millipore
Cat# MAB2166
reference,
Graham, 2006
Peters, 2002
Formulation: liquid, ascites, no preserves
Reactivity:
Reacts in: Rabbit, Human, Monkey, Hamster, Mouse, Rat
others not tested

Immunogen/Epitope

immunogen = Huntingtin fragment from aa 181-810 as a fusion protein

Specificity

Huntingtin Protein. No detectable cross reactivity to other proteins by WB

Comments / Questions

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References

Paper Citations

  1. . Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin. Cell. 2006 Jun 16;125(6):1179-91. PubMed.
  2. . Arfaptin 2 regulates the aggregation of mutant huntingtin protein. Nat Cell Biol. 2002 Mar;4(3):240-5. PubMed.

Further Reading

No Available Further Reading