Clonality: monoclonal
Host: Mouse
Source: (G Dreyfuss
Howard Hugues Medical Institute)
Paper
Reference:
Winton, 2008
Reactivity:
Reacts in: Various vertebrate, Human

Immunogen/Epitope

immunogen = in vivo UV-crosslinked
protein-RNA complexes of poly(A)+hnRNA and
poly(A)+mRNA

Specificity

recognizes hnRNP C₁ and C₂; cellular distribution of the proteins recognized was similar to 2B12; epitopes are different but must be on the same polypeptide chains

Comments / Questions

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References

Paper Citations

1. Winton MJ, Igaz LM, Wong MM, Kwong LK, Trojanowski JQ, Lee VM. Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J Biol Chem. 2008 May 9;283(19):13302-9. PubMed.

External Citations

1. G Dreyfuss
2. Paper

Further Reading

No Available Further Reading