Antibody

GSK-3β pSer9 (5B3)

Clonality: monoclonal
Host: Rabbit
Isotype: IgG
Methods: IC, IF, IH, WB
Source: Cell Signaling
Cat# 9323
Reference:
Zempel H, 2010
Formulation: liquid, HEPES, saline, BSA, glycerol, azide
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat

Immunogen/Epitope

immunogen = a synthetic phosphopeptide corresponding to residues around Ser9 of human GSK-3β

Specificity

recognizes endogenous levels of GSK-3 only when phosphorylated at Ser9 of GSK-3β may cross weakly with the phosphorylated form of GSK-3α due to high sequence homology

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References

Paper Citations

  1. . Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.

Further Reading

No Available Further Reading