Antibody

GSK-3β (7/GSK-3b)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: BD Transduction
Cat# 610201/2
References:
Zempel H, 2010
Papasozo- menos, 2002
Formulation: aqueous buffered solution, glycerol, BSA, azide
Reactivity:
Reacts in: Dog, Chicken, Human, Mouse, Rat

Immunogen/Epitope

Immunogen = rat GSK-3β, aa 1-160

Specificity

detects GSK3β, 46 kDa

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References

Paper Citations

  1. Zempel H, Thies E, Mandelkow E, Mandelkow EM. Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.
  2. Papasozomenos SC, Shanavas A. Testosterone prevents the heat shock-induced overactivation of glycogen synthase kinase-3 beta but not of cyclin-dependent kinase 5 and c-Jun NH2-terminal kinase and concomitantly abolishes hyperphosphorylation of tau: implications for Alzheimer's disease. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1140-5. PubMed.

Further Reading

No Available Further Reading