Antibody

GluR-1

Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Methods: IF, WB
Source: Calbiochem EMD Biosciences
Cat# PC246
References:
Lee, KJ, 2010
Giorgi, 2007
Nakamoto, 2007
Schmidt, 2007
Formulation: liquid, phosphate buffer, gelatin, azide
Reactivity:
Reacts in: Rat

Immunogen/Epitope

Immunogen = synthetic peptide (RTSDSRDH TRVDWKR) corresp. to aa
271-285 of rat GluR1 (numbered from the signal peptide)

Specificity

recognizes the ~105-107 kDa GluR1 protein. Also cross-reacts with a 50 kDa protein in rat brain extracts

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References

Paper Citations

  1. Lee KJ, Moussa CE, Lee Y, Sung Y, Howell BW, Turner RS, Pak DT, Hoe HS. Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines. Neuroscience. 2010 Aug 11;169(1):344-56. PubMed.
  2. Giorgi C, Yeo GW, Stone ME, Katz DB, Burge C, Turrigiano G, Moore MJ. The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression. Cell. 2007 Jul 13;130(1):179-91. PubMed.
  3. Nakamoto M, Nalavadi V, Epstein MP, Narayanan U, Bassell GJ, Warren ST. Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15537-42. PubMed.
  4. Schmidt V, Sporbert A, Rohe M, Reimer T, Rehm A, Andersen OM, Willnow TE. SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1. J Biol Chem. 2007 Nov 9;282(45):32956-64. PubMed.

Further Reading

No Available Further Reading