Antibody

GFAP (6F2)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1κ
Source: DAKO
cat# M0761
References:
Ding, 2008
Cherny 2001
Formulation: liquid, supernat, Tris, azide
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = GFAP from human brain

Specificity

detects 52kDa intermediate filament protein GFAP in cytoplasm in brain and spinal cord; in astrocytes, depressed in cytomas

Note

diagnosis

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References

Paper Citations

  1. Ding Y, Qiao A, Wang Z, Goodwin JS, Lee ES, Block ML, Allsbrook M, McDonald MP, Fan GH. Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci. 2008 Nov 5;28(45):11622-34. PubMed.
  2. Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, Zheng H, Tanzi RE, Masters CL, Bush AI. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron. 2001 Jun;30(3):665-76. PubMed.

Further Reading

No Available Further Reading