Antibody

Galactocerebroside (mGalC)

Clonality: monoclonal
Host: Mouse
Isotype: IgG3
Methods: ELISA, IC, IH, WB
Source: Chemicon and Upstate are Millipore
Cat# MAB342
Reference:
Blurton-Jones, 2009
Formulation: liquid, purified, Potassium Phosphate, saline, azide
Reactivity:
Reacts in: Bovine, Rabbit, Chicken, Human, Mouse, Rat

Immunogen/Epitope

immunogen = Synaptic plasma membranes from bovine hippocampus

Specificity

recognizes Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids. Cross-reacts with the sulfatide ester of GalC, but to a 16-fold lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically with oligodendrocytes and Schwann cellsGalC is a very useful, specific marker for oligodendroglial lineage

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References

Paper Citations

  1. . Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13594-9. PubMed.

Further Reading

No Available Further Reading