Antibody

FMRP (1C3)

Clonality: monoclonal
Host: Mouse
Isotype: IgG1κ
Methods: ELISA, IC, IH, WB
Source: Chemicon and Upstate are Millipore
Cat# MAB2160
Reference:
Giorgi, 2007
Zalfa, 2007
Hayashi, 2007
Formulation: liquid, ascites, no preservative
Reactivity:
Reacts in: Zebra fish, Human, Monkey, Mouse, Rat

Immunogen/Epitope

immunogen = fusion protein with a full length human FMRP (epitope is localized in the N-terminal half )

Specificity

detects FMRP. Cross reaction with FXR protein may be detected in cases of high expression of the latter proteins

Note

not FC or IP

Comments / Questions

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References

Paper Citations

  1. . The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression. Cell. 2007 Jul 13;130(1):179-91. PubMed.
  2. . A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nat Neurosci. 2007 May;10(5):578-87. PubMed.
  3. . Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11489-94. PubMed.

Further Reading

No Available Further Reading