Antibody

ERK1/2 p44/42 phos Thr202/Tyr204 (D13.14.4E)

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Clonality: monoclonal
Host: Rabbit
Isotype: IgG
Source: Cell Signaling
Cat# 4284
Formulation: liquid, BSA, HEPES, NaCl, glycerol, Alexa Fluor® 647 conj.
Reactivity:
Reacts in: Bovine, Mink, Zebra fish, Pig, Human, Monkey, Hamster, Mouse, Rat, Drosophila

Immunogen/Epitope

Immunogen = a synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human p44 MAP kinase

Specificity

Recognizes endogenous levels of p42/44 MAP kinase (ERK1/2) only when either dually phosphorylated at Thr202 and Tyr204 of Erk1 (Thr185 and Tyr187 of Erk2), or singularly phosphorylated at Thr202. This antibody does not cross-react with the corresponding phosphorylated residues of either JNK/SAPK or p38 MAP kinases.

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Further Reading

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