Antibody

ERK1/2 p44/42 MAPK (L34F12)

Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: FC, IH, IP, WB
Source: Cell Signaling
Cat# 4696
Reference:
Zempel H, 2010
Formulation: liquid, HEPES, NaCl, BSA, glycerol, azide
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat

Immunogen/Epitope

Immunogen = synthetic peptide derived from the sequences of rat p44/42 MAP kinase

Specificity

Recognizes endogenous levels of total p44/42 MAP kinase (ERK1/2) protein. Does not cross-react with JNK/SAPK or p38 MAP kinase.

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References

Paper Citations

  1. . Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J Neurosci. 2010 Sep 8;30(36):11938-50. PubMed.

Further Reading

No Available Further Reading