Antibody

ERK1 & ERK2 phos Thr185/Tyr187 (AMK1)

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Clonality: monoclonal
Host: Mouse
Source: Biomol Enzo Life Sciences
Cat# MA-1366
Formulation: PBS, BSA, azide, lyophilized
Reactivity:
Reacts in: Human, Mouse, Rat, Bovine

Immunogen/Epitope

Immunogen = phosphopeptide containing the motif pThr-Glu-pTyr conjugated to a carrier protein

Specificity

Recognizes activated mammalian ERK1/2 and exhibits no reactivity with non-activated MAP kinases. In ELISA and dot blotting studies with synthetic peptides as antigens, AMK1 does not react with the TEY motif when only the Thr or Tyr is phosphorylated. Moreover, no cross with the phospho. motifs of SAPK/JNK (Thr-Pro-Tyr) or p38 kinases (Thr-Gly-Tyr)

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