Antibody

CD11b /Mac-1α (M1/70)

Clonality: monoclonal
Host: Rat
Isotype: IgG2b
Methods: FC
Source: BD Pharmingen
Cat# 557657
Formulation: aqueous buffered solution, affinity purified, stabilizer, azide, APC-Cy7 conj.<br />Also available PerCP-Cy5.5 conj, #550993<br />PE-Cy™7 conj, #552850<br />APC conj, #553312<br />PE conj, #553311
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes

Specificity

reacts with CD11b; reportedly blocks cell adherence and C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported

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References

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Further Reading

No Available Further Reading