Clonality: monoclonal
Host: Rat
Isotype: IgG_2b
Source: AbD Serotec
Cat# MCA711
References:
Heneka, 2010
Lee, 2007
Formulation: liquid, purified IgG, PBS, azide<br />See <a href="http://www.abdserotec.com/catalog/search.aspx?searchType=ENTITY&amp;search=MCA711&amp;cat=&amp;type=&amp;page=&amp;" target="_new">list</a> of other formats
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = Thioglycollate elicted Peritoneal Macrophages (TPM)

Specificity

recognizes mouse complement type 3 receptor (CR3) and precipitates a heterodimer of 165 and 95kD

Comments / Questions

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References

Paper Citations

1. Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. PubMed.

External Citations

1. Lee, 2007
2. list

Further Reading

No Available Further Reading