Antibody

Caspase-3, full-length and cleaved Asp175 (3G2)

Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: WB
Source: Cell Signaling
Cat# 9668
Reference:
Xie et al,, 2007
Formulation: liquid, HEPES, NaCl, BSA, glycerol
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = synthetic peptide (KLH-coupled) corresponding to amino acids 28-44 of human caspase-3

Specificity

detects endogenous levels of full length (35 kDa) and the large fragment (17/19 kDa) of caspase-3 resulting from cleavage at aspartic acid 175

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References

Paper Citations

  1. . The inhalation anesthetic isoflurane induces a vicious cycle of apoptosis and amyloid beta-protein accumulation. J Neurosci. 2007 Feb 7;27(6):1247-54. PubMed.

Further Reading

No Available Further Reading