Antibody

Caspase-3, activated, cleaved Asp175

Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Methods: FC, IC, IF, IH, WB
Source: Cell Signaling
Cat# 9661
References:
Burré J, 2010
Wilcock, 2008
Breunig, 2007
Formulation: liquid, protein-A, affinity purified
Reactivity:
Reacts in: Bovine, Human, Monkey, Mouse, Rat
expect dog, pig

Immunogen/Epitope

immunogen = synthetic peptide (KLH-coupled) corresp. to amino-terminal residues adjacent to Asp175 of human caspase-3

Specificity

detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175; does not recognize full length caspase-3 or other cleaved caspases

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References

Paper Citations

  1. . Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science. 2010 Sep 24;329(5999):1663-7. PubMed.
  2. . Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2. J Neurosci. 2008 Feb 13;28(7):1537-45. PubMed.
  3. . Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20558-63. PubMed.

Further Reading

No Available Further Reading