Antibody

Beta-Secretase-1

Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Methods: ELISA, IP, WB
Source: A B R - Thermo Scientific
Cat# PA1-757
References:
O'Connor, 2008
Kim, 2007
Formulation: liquid, affinity purified, PBS, BSA, azide
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = synthetic peptide, C L R Q Q H D D F A D D I S L L K, aa485-501 of human β-secretase 1

Specificity

transfected β-secretase 1

Comments / Questions

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References

Paper Citations

  1. . Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron. 2008 Dec 26;60(6):988-1009. PubMed.
  2. . BACE1 regulates voltage-gated sodium channels and neuronal activity. Nat Cell Biol. 2007 Jul;9(7):755-64. PubMed.

Further Reading

No Available Further Reading