Antibody

Beta Amyloid (6F/3D)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Novocastra
Cat# NCL-B-Amyloid
References:
Koivunen, 2008
Holmes, 2008
Lewis, 2001
Formulation: lyophilized, supernatant, azide
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = synthetic peptide on human beta amyloid molecule

Specificity

beta amyloid

Note

not frozen tissue

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References

Paper Citations

  1. Koivunen J, Verkkoniemi A, Aalto S, Paetau A, Ahonen JP, Viitanen M, Någren K, Rokka J, Haaparanta M, Kalimo H, Rinne JO. PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease. Brain. 2008 Jul;131(Pt 7):1845-53. PubMed.
  2. Holmes C, Boche D, Wilkinson D, Yadegarfar G, Hopkins V, Bayer A, Jones RW, Bullock R, Love S, Neal JW, Zotova E, Nicoll JA. Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet. 2008 Jul 19;372(9634):216-23. PubMed.
  3. Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, Jones G, Yen SH, Sahara N, Skipper L, Yager D, Eckman C, Hardy J, Hutton M, McGowan E. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science. 2001 Aug 24;293(5534):1487-91. PubMed.

Further Reading