Antibody

BACE1 (3D5)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: BACE-Cat1
Reference:
O'Connor, 2008
Formulation: affinity purified
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = N terminus catalytic domain (amino acids 46–460) with N-terminal 6xHis tag

Specificity

recognizes the catalytic domain of BACE-1.Paper by Zhao et al., 2007

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References

Paper Citations

  1. O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hébert SS, De Strooper B, Haass C, Bennett DA, Vassar R. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron. 2008 Dec 26;60(6):988-1009. PubMed.

External Citations

  1. Paper

Further Reading

No Available Further Reading