Clonality: polyclonal
Host: Rabbit
Source: anti-amyloid beta FCA3340
(Frédéric Checler,
Centre National de la Recherche Scientifique),
Paper
Reference:
Gandy, 2010
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = synthetic octapeptide Cys-GLMVGGVV, mimicing the C-terminal end of Aβ 40, coupled to either BSA or KLH

Specificity

amyloid-beta 40; labels leptomeningeal and cortical arterioles;little or no cross with Aβ 42

Comments / Questions

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References

Paper Citations

1. Gandy S, Simon AJ, Steele JW, Lublin AL, Lah JJ, Walker LC, Levey AI, Krafft GA, Levy E, Checler F, Glabe C, Bilker WB, Abel T, Schmeidler J, Ehrlich ME. Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers. Ann Neurol. 2010 Aug;68(2):220-30. PubMed.

External Citations

1. Frédéric Checler
2. Paper

Further Reading