Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Sigma Aldrich
Cat# A8967
References:
Lee, KJ, 2010
Muresan, 2009
Hoe, 2009
Formulation: IgG frac, PBS, azide
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = synthetic, aa 46-60 of the N terminus of APP₆₉₅

Specificity

APP₆₉₅, APP₇₅₁ and APP₇₇₀

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References

Paper Citations

1. Lee KJ, Moussa CE, Lee Y, Sung Y, Howell BW, Turner RS, Pak DT, Hoe HS. Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines. Neuroscience. 2010 Aug 11;169(1):344-56. PubMed.
2. Muresan V, Varvel NH, Lamb BT, Muresan Z. The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites. J Neurosci. 2009 Mar 18;29(11):3565-78. PubMed.
3. Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW. Interaction of reelin with amyloid precursor protein promotes neurite outgrowth. J Neurosci. 2009 Jun 10;29(23):7459-73. PubMed.

Further Reading