Antibody

APP, CT

Tools

Back to the Top

Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Sigma Aldrich
Cat# A8717
References:
Kim, 2009
Stante, 2009
Ding, 2008
Li, 2007
Guenette, 2006
Feng, 2006
Formulation: IgG frac, PBS, azide
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = synthetic peptide corr. to aa 676-695 on C-terminal of APP695

Specificity

APP695, APP751 and APP770

Comments / Questions

No Available Comments

Make a comment or submit a question

To make a comment you must login or register.

References

Paper Citations

  1. Kim M, Suh J, Romano D, Truong MH, Mullin K, Hooli B, Norton D, Tesco G, Elliott K, Wagner SL, Moir RD, Becker KD, Tanzi RE. Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. Hum Mol Genet. 2009 Oct 15;18(20):3987-96. PubMed.
  2. Stante M, Minopoli G, Passaro F, Raia M, Vecchio LD, Russo T. Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5093-8. PubMed.
  3. Ding Y, Qiao A, Wang Z, Goodwin JS, Lee ES, Block ML, Allsbrook M, McDonald MP, Fan GH. Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci. 2008 Nov 5;28(45):11622-34. PubMed.
  4. Li A, Xie Z, Dong Y, McKay KM, McKee ML, Tanzi RE. Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes. Hum Mol Genet. 2007 Nov 1;16(21):2626-39. PubMed.
  5. Guénette S, Chang Y, Hiesberger T, Richardson JA, Eckman CB, Eckman EA, Hammer RE, Herz J. Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J. 2006 Jan 25;25(2):420-31. PubMed.
  6. Feng X, Zhao P, He Y, Zuo Z. Allele-specific silencing of Alzheimer's disease genes: the amyloid precursor protein genes with Swedish or London mutations. Gene. 2006 Apr 12;371(1):68-74. PubMed.

Further Reading