Apo E

Clonality: polyclonal
Host: Goat
Methods: ELISA, IH, IP
Source: Calbiochem EMD Biosciences
Cat# 178479
Kim, 2009
Wahrle, 2008
Buttini, 2002
Liu, 2007
Formulation: serum, Tris-HCl, NaCl, azide
Reacts in: Human, Mouse, Rat


immunogen = purified recombinant human Apo-E


recognizes ApoE; no cross-reaction with other apolipoproteins

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Paper Citations

  1. . Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance. Neuron. 2009 Dec 10;64(5):632-44. PubMed.
  2. . Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest. 2008 Feb;118(2):671-82. PubMed.
  3. . Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation. J Neurosci. 2002 Dec 15;22(24):10539-48. PubMed.
  4. . Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron. 2007 Oct 4;56(1):66-78. PubMed.

Further Reading