Antibody
Amyloid β (252Q6)
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Clonality: monoclonal
Host: Mouse
Isotype: IgG1, κ
Source: Biosource Invitrogen
cat# AMB0062
Reference:
Bell, 2009
Burton, 2008
Formulation: liquid, PBS, BSA, azide, affinity purified
Reactivity:
Reacts in: Mouse, Rat
low with human
Immunogen/Epitope
immunogen = chemically synthesized peptide derived from aa 1-20 of mouse Aβ. This region is conserved in rat Aβ
Specificity
Amyloid β as well as APP
Note
capture antibody
References
Paper Citations
- Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV. SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nat Cell Biol. 2009 Feb;11(2):143-53. PubMed.
- Burton CR, Meredith JE, Barten DM, Goldstein ME, Krause CM, Kieras CJ, Sisk L, Iben LG, Polson C, Thompson MW, Lin XA, Corsa J, Fiedler T, Pierdomenico M, Cao Y, Roach AH, Cantone JL, Ford MJ, Drexler DM, Olson RE, Yang MG, Bergstrom CP, McElhone KE, Bronson JJ, Macor JE, Blat Y, Grafstrom RH, Stern AM, Seiffert DA, Zaczek R, Albright CF, Toyn JH. The amyloid-beta rise and gamma-secretase inhibitor potency depend on the level of substrate expression. J Biol Chem. 2008 Aug 22;283(34):22992-3003. PubMed.
Further Reading
No Available Further Reading
Comments / Questions
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