Source: Cell Signaling
Formulation: liquid, protein-A and affinity purified, HEPES, saline, BSA, glycerol
Reacts in: Human, Monkey, Mouse, Rat
immunogen = synthetic phospho-peptide (KLH-coupled) corresponding to residues surrounding Thr37 and Thr46 of mouse 4E-BP1
detects endogenous levels of 4E-BP1 only when phosphorylated at Thr37 and/or Thr46; may cross-react with 4E-BP2 and 4E-BP3 when phosphor. at equivalent sites
- Hoeffer CA, Tang W, Wong H, Santillan A, Patterson RJ, Martinez LA, Tejada-Simon MV, Paylor R, Hamilton SL, Klann E. Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron. 2008 Dec 10;60(5):832-45. PubMed.
No Available Further Reading