Alzpedia
C9ORF72
Synonyms: chromosome 9 open reading frame 72, FTDALS, ALSFTD
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References
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Further Reading
News
- C9ORF72 Function: Is the ALS Protein a Membrane Traffic Cop?
- Researchers Revel in C9ORF72 Advances at RNA Symposium
- Sense, Antisense: C9ORF72 Makes Both Forms of RNA, Peptides
- Second Study Confirms Antisense Oligonucleotides Bust RNA Aggregates
- RNA Deposits Confer Toxicity in C9ORF72 ALS
- Brain Imaging Distinguishes C9ORF72 From Other Types of ALS
- Methylation a Turn Off for Disease Gene C9ORF72?
- ALS GWAS Confirm Chromosome 9 Risk Factor—But What Is It?
- Corrupt Code: DNA Repeats Are Common Cause for ALS and FTD
- C9ORF72 Steals the Show at Frontotemporal Dementia Meeting
- Chicago—Dynamic Repeats: C9ORF72 Expands and Shrinks in ALS
- RNA Twist: C9ORF72 Intron Expansion Makes Aggregating Protein
- Second Study Sees Intron in FTLD Gene Translated
Papers
- van Blitterswijk M, Dejesus-Hernandez M, Rademakers R. How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: can we learn from other noncoding repeat expansion disorders?. Curr Opin Neurol. 2012 Dec;25(6):689-700. PubMed.
- Van Langenhove T, van der Zee J, Van Broeckhoven C. The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum. Ann Med. 2012 Dec;44(8):817-28. Epub 2012 Mar 16 PubMed.
- Rademakers R, van Blitterswijk M. Motor neuron disease in 2012: Novel causal genes and disease modifiers. Nat Rev Neurol. 2013 Feb;9(2):63-4. PubMed.
- Rademakers R, Neumann M, Mackenzie IR. Advances in understanding the molecular basis of frontotemporal dementia. Nat Rev Neurol. 2012 Jun 26;8(8):423-34. PubMed.
- Goedert M, Ghetti B, Spillantini MG. Frontotemporal dementia: implications for understanding Alzheimer disease. Cold Spring Harb Perspect Med. 2012 Feb;2(2):a006254. PubMed.