For FTD Drug Development, a Q&A With Regulators
Regulators and industry scientists, and other steering committee members from the FTSG submitted questions to the U.S. Food and Drug Administration...
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Regulators and industry scientists, and other steering committee members from the FTSG submitted questions to the U.S. Food and Drug Administration...
Given that DNA methylation and cognition both decline with age, is there a protein that links the two?...
Having a few excess polyglutamine codons—but not a lot—in the gene ataxin-2 predisposes a person to ALS, and scientists are just starting to figure out how...
Nursemaid oligodendrocytes care for neuronal axons not only by wrapping them in insulating myelin, but also by feeding them lactate...
In AD therapy, it may be time for an alternative target to shine: the α7 nicotinic acetylcholine receptor...
A paper in today’s Cell suggests that at least one type of amyloid plays a crucial role in physiologic signaling...
Alzheimer’s disease is usually thought of as a disorder of two proteins, Aβ and tau, but α-synuclein may be equally important to the disease process...
Beth Stevens, Children’s Hospital, Boston, was one of 96 scientists and engineers who received Presidential Early Career Award for Scientists and Engineers...
Researchers report that AD-associated decline slows with advancing age, while “normal” aging-associated decline picks up...
Researchers have shown that the CSF goes into the brain along very specific anatomical structures...
Researchers measured Aβ distribution in the barrel cortex of AD mice, and found that plaques tended to form between the barrels, a region rich in inhibitory interneurons...
What can big data do for medicine?...
The crimes of soluble Aβ continue to grow...
Native to Chile, degus develop pathological hallmarks of Alzheimer’s disease, including Aβ and tau deposits...
Researchers have discovered a gene that adjusts the course of amyotrophic lateral sclerosis, a fatal and rapidly progressing neurodegenerative disease...
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