GV-971, an oligosaccharide derived from marine kelp, was approved to treat AD in China. Preclinical studies suggest the drug soothes neuroinflammation by balancing the gut microbiome.
Overexpressing the endosomal activator in neurons not only caused those organelles to swell, but also bungled synaptic transmission, goaded hyperphosphorylation of tau, and destroyed cholinergic neurons.
When the agency sent warning letters to 17 companies that falsely advertised cures and preventions for AD, most took down exaggerated claims. But can regulations stay ahead of the market?
Early in the course of Alzheimer disease, blockages in axonal traffic lead to sick axons swollen with the jumbled pile-up of traffic components. The blockages precede...
There has been considerable excitement generated by findings that statins, which lower plasma cholesterol, may help protect against Alzheimer disease...
The 5th Clinical Trials in Alzheimer’s Disease conference offered new data from ongoing analyses of the Phase 3 programs on solanezumab and bapineuzumab...
Is the glass half empty or half full? Alzheimer disease clinicians might be asking themselves that question after seeing the long-awaited results of...
This week's PNAS early online edition reports that, depending on the diet, even minor amounts of copper can lead to both amyloid plaques and a memory deficit in rabbits...