<strong>Raj Kalaria</strong> and <strong>Francine Gervais</strong> organized the Second International Conference on cerebral amyloid angiopathy (CAA), held December 4 to 6 in Newcastle upon Tyne, England...
Elderly men with symptoms of ataxia and intention tremor may actually have a disorder related to fragile X syndrome, a common form of mental retardation in children. These men show signs of...
Oxidative stress has been implicated as a factor in the neurodegeneration that leads to a variety of neurologic disorders, including Parkinson's and Huntington's diseases...
Apolipoprotein E (ApoE) was first identified in the 1970s as playing a role in regulating plasma cholesterol levels, and in genetic hyperlipoproteinemias...
At least nine neurodegenerative disorders—Huntington’s disease being perhaps the best known—are caused by the reiteration of glutamine-coding CAG trinucleotides in the genome...
Figuring out what high levels of brain amyloid mean for otherwise healthy older people was a prime focus of the Human Amyloid Imaging (HAI) conference...
The earliest pathological underpinnings of Alzheimer disease often precede symptoms by untold numbers of years, presenting researchers with a two-edged sword...
With mounting evidence that AD can silently ravage the brain years before symptoms emerge, the race is on to develop compounds that can detect preclinical changes...