Data on ASOs, presented recently at the annual meeting of the American Academy of Neurology, depict RNA-based therapies as broadly on the rise in neurodegenerative diseases.
At Quebec conference, researchers considered multiple aspects of herpesvirus biology that may come in to play in AD.
In patient-derived neurons, tau mutations scupper lysosomes and SORLA shunts APP through different types of endosomes.
Can genetics please parse the confusing spectrum of frontotemporal dementias? Whole genome sequences make a start.