New Gene for ALS: RNA Regulation May Be Common Culprit
Scientists have uncovered a fresh clue in the mystery that is amyotrophic lateral sclerosis...
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Scientists have uncovered a fresh clue in the mystery that is amyotrophic lateral sclerosis...
Everyone knows that smoking is bad for you. But there is some evidence, both epidemiological and molecular, that smokers are at reduced risk for neurodegenerative diseases such as Alzheimer's (AD) and Parkinson's (PD)...
Experimental evidence and plain common sense tell us that neurons lose activity in Alzheimer disease...
A large, collaborative group led by Julie Andersen at the Buck Institute for Research in Aging, Novato, California, demonstrates that lowering the bioavailability of iron—both systemically and in dopaminergic neurons—protects mice against chemically induced Parkinson's...
The tight barrier between brain and blood vessels guards the brain from harm, but also frustrates scientists trying to deliver therapeutic molecules to the CNS...
Despite its spot on top of the pile of genetic risk factors for late onset AD, ApoE has remained an enigma on the pathophysiological level...
Like good cholesterol and bad cholesterol, the Alzheimer's community has realized that there may also be good Aβ and bad Aβ...
Pfizer conceded that results of the first of four Phase 3 trials of intravenous bapineuzumab failed to meet its co-primary endpoints in patients with mild to moderate AD...
Rare mutations in a microglial receptor contribute as much to Alzheimer’s risk as does the more common ApoE4 genotype...
Chalk another one up for the “not-all-about-amyloid” camp...
Keeping brain amyloid-β (Aβ) levels in check means controlling both the means of production and the method of disposal...
A foursome of papers on ApoE deserves attention this week. Having plenty of ApoE is a prerequisite for...
Plasma cholesterol measurements have done wonders for cardiovascular disease management...
A foursome of papers in the February 17 Archives of Neurology continues the shifting debates about three epidemiological questions in Alzheimer’s research...
Thanks to a new imaging technology, researchers discovered that amyloid plaques can literally show up overnight and grow to their full size in just a few days...