An Ultra-High-Resolution, 3D View of the Human Brain
An ultra-high-resolution 3D map of the human brain promises to help scientists studying neuroanatomy, neurosurgery, neurodegenerative disease, and more.
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An ultra-high-resolution 3D map of the human brain promises to help scientists studying neuroanatomy, neurosurgery, neurodegenerative disease, and more.
The experimental drug NitroMemantine protects synapses from Aβ oligomer toxicity in mice by blocking extrasynaptic NMDA receptors.
Eating fewer saturated fats and simple sugars reduces harmful forms of Aβ in the cerebrospinal fluid, scientists report.
In a series of eight reviews, titled "Focus on Neurotechniques," researchers describe how approaches such as optogenetics and stem cells are revolutionizing neuroscience.
Similar to Alzheimer's disease, PD dementia begins with subtle deficits in cognition that progress to symptoms recognizable as mild cognitive impairment.
By looking for structural DNA variations in Alzheimer’s families, researchers identified 18 new genes that may play a role in AD pathology.
Using hormone therapy early in menopause neither helps nor harms cognition, researchers report.
Magnetic resonance spectroscopy bolsters hypothesis that ALS results from too much glutamate and too little GABA
Growing evidence suggests that innate immune cells prevent or slow Alzheimer's disease by chewing up Aβ and promoting its clearance.
Courts in Europe revoked a patent that laid claim to all passive immunotherapy for Alzheimer’s disease, clearing the way for others to freely pursue this strategy...
A newly discovered lipid modification on the amyloid precursor protein may mark it for amyloidogenic processing...
Researchers identify the Aβ-binding scavenger receptor CD36 as a key regulator of macrophage inflammasome responses...
Scientists have discovered yet another function for β-secretase (BACE1), the enzyme that kick-starts amyloidogenic processing of the amyloid-β precursor protein...
Mouse studies point to a new pathway that mediates motor neuron disease caused by mutations in superoxide dismutase 1.
The FDA and EMA have endorsed a new tool for modeling AD clinical trials to select the best design, potentially speeding up drug discovery.
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