Being Pleasantly Plump: Way to Live Longest with ALS?
Researchers report that a high body mass index (BMI), indicating mild obesity, was linked to survival in ALS...
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Not All Stem Cells Are Created Equal: Immune Rejection of iPSCs
Could induced pluripotent stem cells (iPSCs) be just as good as embryonic stem cells (ESCs) for therapeutic use?...
ApoE Disrupts Brain Networks, Helps Microglia Clear Aβ
Aside from its crystal-clear status as top risk gene for late-onset Alzheimer’s disease (LOAD), much mystery still shrouds apolipoprotein E...
Interferon-γ’s Interference May Cause Parkinsonism
Could today’s viral encephalitis become tomorrow’s Parkinson’s disease?...
Gladstone Workshop: Tau and Tauopathies: Pathogenic Mechanisms
San Francisco: Gladstone Institute Hosts Tau Powwow San Francisco: Making Tau Toxic—Post-translational Changes Galore San Francisco: Is Tau Reduction a Good Thing? San Francisco: Tau—Time to Shine as Therapeutic Target? Tauists are having their heyday. Fi
San Francisco: Tau—Time to Shine as Therapeutic Target?
Attendees bonded over a common research interest—the protein tau and its role in neurodegeneration...
Led by ALS, Social Networking Comes to Medical Research
Having transformed the way people interact, social networking may be poised to transform medicine as well...
Race Means Nothing, Genes Everything, in Personalized Medicine
Michael Jackson sang, “It don’t matter if you’re black or white”—and that goes for people in the doctor’s office, too...
Research Brief: Last Word From NIH Panel on AD Prevention
A State-of-the-Science panel convened by the National Institutes of Health found insufficient evidence to recommend any health intervention to prevent AD...
San Francisco: Is Tau Reduction a Good Thing?
Though amyloid-β and tau stand as the pathological hallmarks of AD, only recently have scientists gained insight into how the two could be linked mechanistically...
San Francisco: Making Tau Toxic—Post-translational Changes Galore
Given its correlation with Alzheimer’s disease progression, tau hyperphosphorylation has long commanded the field’s attention...
Little by Little—Standardizing, Validating Those Biomarkers
Biomarkers stand poised to transform Alzheimer’s research, but scientists first must iron out pesky technical issues and ensure that markers give reliable, repeatable results...
Research Brief: Early Steps in Aβ’s Synaptic Attack
Scientists know that Aβ harms synaptic signaling early in Alzheimer’s disease, but how does the peptide do it?...
Cognitive Impairment, Dementia Keep Rising in the Oldest Old
Oldest-old survivor stories notwithstanding, mild cognitive problems, as well as full-blown dementia, are common among women 85 years and older...
San Francisco: Gladstone Institute Hosts Tau Powwow
In San Francisco, attendees discussed how tau goes awry...
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