Single-Blind Trial: Diabetes Drug Helps Parkinson’s, Maybe
Could an approved diabetes medication treat Parkinson’s disease?...
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G8 to Set Sights on Dementia
This June, leaders from the globe’s eight richest countries, the G8, will assemble to discuss major economic issues—among them, the rising threat of dementia in aging populations...
Does Shrinking Temporal Lobe Make AD Patients Overly Sensitive?
Though typically seen as a cognitive disorder, Alzheimer’s disease can throw emotions off kilter, making people unusually sensitive to others’ feelings and moods...
The Power of Three: Genetic Trios Yield ALS Gene Candidates
The May 26 Nature Neuroscience online debuts 25 new candidate genes for amyotrophic lateral sclerosis...
Alzheimer’s Disease Snags High-Profile Prize
The focus of the next XPRIZE is Alzheimer’s disease...
Limited Protein Shapes May Explain Drug Side Effects
A new study explains why many drugs come with similar side effects...
A Protein-Based Study of Parkinsonism’s Incidence
In a study, scientists included rare types of parkinsonism and categorized them by their underlying proteinopathy...
Finally, Therapies Targeting Huntingtin Poised for Clinic
Twenty years after the identification of the mutant gene that causes Huntington’s disease, scientists are ready to take therapies that target it into human trials...
Aβ Fibrils Drive Oligomer Formation, New Model Suggests
As attention shifts toward free-floating Aβ oligomers as the prime molecular culprits in AD, there is still plenty of confusion over the role of fibrillar amyloid...
Bexarotene Revisited: Improves Mouse Memory But No Effect on Plaques
Researchers reported in 2012 that the cancer drug bexarotene swiftly cleared amyloid-β and restored memory in transgenic mouse models of Alzheimer's disease...
Paper Alert: B Vitamins Slow Atrophy in AD Vulnerable Brain Regions
Results of a two-year clinical trial suggest that a mixture of B vitamins slows atrophy up to sevenfold in areas of the brain that are vulnerable to degeneration in AD...
Scientists Create Human Stem Cells by Somatic Cell Nuclear Transfer
Scientists report the first successful generation of human embryonic stem cells via somatic cell nuclear transfer...
Controlling Blood Pressure May Lower Amyloid in ApoE4 Carriers
Scientists report that reducing hypertension may ward off amyloid pathology in people who have the ε4 version of the ApoE gene...
Larry Sparks, of Alzheimer’s-Cholesterol Fame, Dies at 63
Alzheimer's disease researchers expressed sadness this week at the sudden death of Larry Sparks...
Dementia Incidence Said to Drop as Public Health Improves
Are fewer people getting Alzheimer’s disease now than they did 20 years ago?...
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