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Humans Sprout New Neurons

It has long been a dogma of neuroscience that the human brain is born with all the neurons it will ever have, and that those neurons must endure for a lifetime. But evidence has been accumulating...

Neuronal Loss in Mouse Model?

Can transgenic mice serve as a truly useful model for studying Alzheimer's disease? Studies of mice expressing an APP gene mutation that causes a form of familial AD have reported no neuronal loss...

Soccer Bad for Brain

A study published in last month's Neurology reports that professional soccer players are at significantly higher risk for long-term brain injuries that affect their mental function...

Eat That Spinach!

A diet rich in certain fruits and vegetables is known to protect against cancer and heart disease, and now a new animal study suggests nutrition can also stall the decline of brain function...

APP Enhances Mouse Memory

Secreted forms of amyloid precursor protein (APP) may play an important role in the formation and consolidation of memory, according to a study published in today's proceedings of the National Academy of Science...

Nature Online

The British science journal Nature announced that it is becoming a "full-fledged" electronic journal beginning with this week's issue (at <a href=""></a>)...

Casting Doubt on Role of Oxidative Damage in ALS

Mutations in the enzyme for superoxide dismutase (SOD1) have been linked to 15 tp 20 percent of cases of amyotrophic lateral sclerosis (ALS), leading to a theory that the disease results when the defective enzyme allows super oxide radicals to build up...

Mitochondria Key to Glutamate Toxicity

Glutamate is a neurotransmitter that is toxic when too much of it is released by excessive neuronal activity or by brain injury. Some researchers have also proposed that glutamate toxicity drives the neurodegeneration...

How NF-κB Derails Apoptosis

A study published in tomorrow's Science provides new details of how the transcription factor NF-κB protects cells from apoptosis. C.-Y. Wang and colleagues report they have identified four genes that are targets of NF-κB activity...

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