Light SPARKs Neuronal Action Potentials
Imagine being able to turn on and off an individual neuron remotely—without prodding it with electrodes or challenging it with chemicals. Sound like a neuroscientist's dream?...
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Imagine being able to turn on and off an individual neuron remotely—without prodding it with electrodes or challenging it with chemicals. Sound like a neuroscientist's dream?...
Defeating the yokozuna, the highest ranked professional sumo wrestlers, is almost impossible. Stopping sumoylation, the modification of proteins with small ubiquitin-like modifiers (SUMO) may be easier...
The metabolic syndrome—a constellation of cardiovascular and diabetes risk factors—is associated with an increased risk of cognitive decline...
Phosphorylation of the microtubule-associated protein tau may be a good thing because it can speed up microtubule transport, but abnormal phosphorylation...
Television shows about medical examiners and psychological profilers are all the rage these days. Wouldn't you like to see one about “cytological” profilers?...
As many of our readers are aware, there has been a running court battle between Elan Inc., Dublin, Ireland, and the Mayo Foundation for Medical Education and Research...
An important RNA interference (RNAi) milestone was reported today in Nature...
Ever since mammalian adult neurogenesis was confirmed, scientists had hoped to get pluripotent cells of the subventricular zone (SVZ) to become...
Studies on ApoE have exploded since it was discovered that those carrying one copy of ApoE4 allele are more likely to get the disease than...
The more scientists learn about γ-secretase, the crazier it looks to them...
If your plaque-busting molecule is too small to prevent amyloid formation, have it bring along a bigger buddy...
A mouse model that mimics both signature pathologies of Alzheimer disease develops a day-to-day forgetfulness at four months...
Next time you ponder the pros and cons of coal burning power plants, consider this: Mitochondria, our cellular power plants, do a great job keeping us supplied with ATP, but they, too, have emission problems...
Biochemists, cell and molecular biologists, start your engines! You now have another Parkinson protein challenge...
Because insulin degrading enzyme (IDE) also degrades Aβ (as well as the AβPP intracellular domain), it has come under intense scrutiny in AD research...